Satellite Symposia Programmes

Wednesday 23 September 2020 17:15–18:15 (CET)   Sobi Satellite Symposium Agenda

How do I manage systemic juvenile idiopathic arthritis (SJIA)?

Your questions answered with case-based discussions

The symposium will explore two different approaches to the management of SJIA (escalation versus treat to target) within the context of different healthcare systems and resources.

The symposium Chair, Prof. Ramanan, and the speaker panel, will also share their expertise in discussing challenging case studies during a LIVE interactive question and answer session.

Programme

Time	Session	Presenter
17:15–17:20	Welcome	Athimalaipet V. Ramanan (Chair)
17:20–17:30	How do I manage SJIA? A conventional approach: Escalating steps	Seza Özen
17:30–17:40	How do I manage SJIA? An innovative approach: Treat to target	Nico Wulffraat
17:40–18:10	LIVE - How do we manage the difficult-to-treat cases? Case-based panel discussion	All
18:10–18:15	Summary and conclusions	Athimalaipet V. Ramanan

Speaker details

Prof. Athimalaipet V Ramanan (Chair)
Bristol Royal Hospital for Children
Bristol, UK

Prof. Seza Özen
Hacettepe University Hospital
Ankara, Turkey

Prof. Nico Wulffraat
University Medical Center Utrecht
Utrecht, Netherlands

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Thursday 24 September 2020 13:00–14:00 (CET)   Novartis Satellite Symposium Agenda

Unmet Needs in Familial Mediterranean Fever (FMF): Real-Life Data, the Patient Perspective, and the Role of Anti–IL-1 Therapy

Learning Objectives

• Characterise the incidence and impact of colchicine resistance among patients with FMF

• Understand disease burden from the perspective of the patient

• Analyse the long-term clinical and quality-of-life (QoL) data for anti–IL-1 therapy in colchicine-resistant FMF

Programme

13:00 – 13:05 Introduction (Chair: Fabrizio de Benedetti, MD, PhD)

13:05 – 13:20 Resistance to Colchicine in a Multicentric FMF National Cohort (Marco Gattorno, MD)

• Clinical outcomes in an Italian cohort of paediatric and adult patients with FMF (data from the EUROFEVER registry)

• Incidence of colchicine resistance and tolerability as defined by a recent consensus statement

• Quality of life and compliance

13:20 – 13:35 Exploring Patient Perspectives in FMF (Saskya Angevare, Patient Advocate)

• The symptom burden of FMF

• Impact of FMF on patients’ quality of life

• Disease control: patient perception vs physician perception

13:35 – 13:50 The Impact of Anti–IL-1 Therapy in Colchicine-Resistant FMF (Helen Lachmann, MA, MB BChir, MD)

• Long-term efficacy and safety of anti–IL-1β therapy in colchicine-resistant FMF

• Impact of anti–IL-1 therapy on QoL

13:50 – 14:00 Conclusion, Q&A (Fabrizio de Benedetti, MD, PhD; all faculty)

Speakers names and complete details

• Fabrizio de Benedetti, MD, PhD (Chair), Ospedale Pediatrico Bambino Gesù, Rome, Italy
• Marco Gattorno, MD, Center for Autoinflammatory Diseases and Immunodeficiencies, G. Gaslini Research Institute, Genoa, Italy
• Saskya Angevare, Patient Advocate, Autoinflammatory Alliance, KAISZ, ENCA, Amersfoort, Netherlands
• Helen J. Lachmann, MA, MB BChir, MD, University College London, Royal Free Hospital London NHS Foundation Trust, London, United Kingdom

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Thursday 24 September 2020 18:30–19:30   Pfizer Satellite Symposium Agenda

Patient Unmet Need in Polyarticular-Course Juvenile Idiopathic Arthritis: Current Challenges and Future Perspectives

Objectives

• Explore the disease state of polyarticular-course juvenile idiopathic arthritis (pcJIA) and the impact of clinical features, diagnosis and disease activity on patients and caregivers
• Discuss the importance of both the patient perspective and the unmet need for optimising the management of pcJIA
• Consider the potential role of therapeutic options currently in development, including Janus kinase (JAK) inhibitors, in the management of pcJIA

Faculty Details:

• Nicola Ruperto, MD, MPH, IRCCS Istituto Giannina Gaslini, Genoa, Italy
• Alessandro Consolaro, MD, PhD., IRCCS Istituto Giannina Gaslini, University of Genoa, Genoa, Italy
• Flora McErlane, MBChB, MSc, MRCPCH, Royal Victoria Infirmary, Newcastle upon Tyne, UK

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Friday 25 September 2020 16:00–17:00 (CET)   Sobi Satellite Symposium Agenda

MAS, CSS, CRS, and Hyperinflammation: What’s in a Name?

The symposium will:

• Explore the family of conditions under the umbrella term of ‘cytokine storm syndrome’ (CSS), including hyperinflammation, cytokine release syndrome (CRS), and macrophage activation syndrome (MAS)

• Highlight the clinical and laboratory manifestations of several example conditions

• Understand the cytokine dynamics and the clinical evidence supporting translation into potential future targeted therapeutic approaches

Please join the expert panel in a live interactive session to discuss key questions raised during the symposium

Programme

Time	Session	Presenter
16:00–16:05	Welcome and introduction	Paul Brogan (Chair)
16:05–16:10	Nomenclature	Paul Brogan
16:10–16:20	Nuances in presentations: clinical and laboratory	Alexei Grom
16:20–16:30	Understanding the cytokine dynamics	Michael Jordan
16:30–16:40	Targeted approaches: available data	Fabrizio De Benedetti
16:40–16:55	LIVE interactive Q&A	All
16:55–17:00	Summary and close	Chair

Speaker details

Prof. Paul Brogan (Chair)
UCL Institute of Child Health, and Great Ormond Street Hospital NHS Foundation Trust
London, UK

Prof. Alexei Grom
Division of Rheumatology
Cincinnati Children’s Hospital
Cincinnati, OH, USA

Prof. Michael Jordan
Division of Immunobiology and Division of Bone Marrow Transplantation and Immune Deficiency
Cincinnati Children’s Hospital
Cincinnati, OH, USA

Prof. Fabrizio De Benedetti
Department of Rheumatology
IRCCS Ospedale Pediatrico Bambino Gesù
Rome, Italy